Eye Drops

Hyposmolar Eye Drops for Dry Eye Syndrome

Hyposmolar drops for dry eye syndrome based on Ribohyal® (HAr), a new chemical entity developed by Iromed. Ribohyal is indicated for patients experiencing mild to severe dry eye.

  • Patented formulation based on the New Chemical Entity Ribohyal
  • Peer-reviewed clinical trial showing superior efficacy versus the competitors (incl. Osdi, osmolarity, and photophobia)
  • Lasts longer on the ocular surface than competitors (up to 4h), requiring fewer instillations
  • Contact lenses friendly

Ribohyal 0.1%, Vitamine E TPGS 0.2%, Sodium Citrate, Monobasic Sodium Phosphate, Dibasic Sodium Phosphate, Sodium Chloride, Purified Water

  • 10 ml preservative free OSD bottle
  • Class IIB CE Medical Device
  • Shelf life: 3 years
  • Compatible with contact lenses

  • C. Caruso, L. D’Andrea, M. Rinaldi, I. Senese, R. Piscopo, C. Costagliola. “Modified Sodium Hyaluronate conjugated to Riboflavin (HAr® 0.1%) as lubricant eyedrops in the treatment of Dry Eye: a prospective randomised study”. Heliyon 10 (2024) e35527.
Drop Sept Iromed
Drop Sept

Phlogolithic Eye Drops

Ophthalmic solution with proven phlogolithic activity. It effectively serves as an adjuvant in pre-surgical prophylaxis and eye infections, safeguarding and promoting the repair processes of the corneal and conjunctival tissues.

  • Patented formulation
  • Superior efficacy versus competitors
  • Wide supporting literature
  • Contact lenses friendly

Vitamin E TPGS, Dibasic sodium phosphate, Sodium phosphate monobasic, Sodium chloride, Chlorhexidine digluconate, Purified water

  • 10 ml bottle
  • Class IIB CE Medical Device
  • Shelf life: 2 years
  • Compatible with contact lenses

  • Caruso, Eletto, Tosco, Pannetta, Scarinci, Troisi, Porta “Comparative evaluation of antimicrobial, antiamoebic and antiviral efficacy of ophthalmic formulations” Microorganisms 2022, 10, 1156.
  • Caruso, Eletto, Rinaldi, Pacente, Troisi, Semeraro, Dell’Omo, Costagliola “Effectiveness and Safety of Topical Chlorhexidine and Vitamin E TPGS in the Treatment of Acanthamoeba Keratitis: A Survey on 29 Cases” J. Clin. Med. 2020, 9, 3775.
  • Caruso, Porta, Tosco, Eletto, Pacente, Bartollino, Costagliola “A Novel Vitamin E TPGS-Based Formulation Enhances Chlorhexidine Bioavailability in Corneal Layers” Pharmaceutics 2020, 12, 642.
Drop Defence
Drop Defence logo

Anti UV and anti blue Light eye drops

Shielding action against UV & Blue Light prolonged exposure, especially indicated for individuals affected by or at risk of macular degeneration (AMD).

  • Proven shielding action against UV and harmful Blue Light
  • Long lasting action
  • Patented formulation
  • Certified as Personal Protective Equipment (PPE)
  • Indications included in the leaflet & supported by multiple publications
  • Preservative free
  • Contact lenses friendly

Riboflavin sodium phosphate 0.05%, Sodium chloride, Vitamin E TPGS, Sodium phosphate bibasic dodecahydrate, Sodium hyaluronate, Methyl Sulfonyl Methane, Sodium phosphate monobasic monohydrate, L-proline, L-glycine, L-leucine, L-lysine chlorhydrate, Purified water

  • 10 ml preservative free OSD bottle
  • Class IIB CE Medical Device
  • Shelf life: 3 years
  • Compatible with contact lenses

  • Palazzo M, Vizzarri F, et Al. “Corneal UV Protective Effects of a Topical Antioxidant Formulation: A Pilot Study on In Vivo Rabbits.” J. Mol. Sci. 2020, 21(15), 5426.
  • Di Nezza F, Caruso C, et Al. “Reaction-diffusion model as framework for understanding the role of riboflavin in “eye defence” formulations.” RSC Adv., 2020, 10, 14965.
  • Bartollino S., Palazzo M., et Al. “Effects of an antioxidant protective topical formulation on retinal tissue of UV-exposed rabbits.” Int Ophthalmol 2020.
  • Vizzarri F, Palazzo M, et Al. “Effects of an antioxidant protective topical formulation on eye exposed to ultraviolet-irradiation: a study in rabbit animal model.” Physiol Res. 2018 Mar 12.
Drop Therapeutic
Drop Therapeutic logo

For Tear Film Dysfunctions

Ophthalmic solution for tear film dysfunctions and pre/post-surgical patients, including refractive surgery and corneal cross-linking treatments.

  • Patented formulation
  • Wide indications as per leaflet
  • Preservative free
  • Contact lenses friendly

Riboflavin sodium phosphate 0.075%, Sodium chloride, Vitamin E TPGS, Sodium phosphate bibasic dodecahydrate, Sodium hyaluronate, Sodium phosphate monobasic monohydrate, L-proline, L-glycine, L-leucine, L-lysine chlorhydrate, Purified water

  • 10 ml preservative free OSD bottle
  • Class IIB CE Medical Device
  • Shelf life: 3 years
  • Compatible with contact lenses
Drop Tonic
Drop Tonic logo

Hypertonic Drops for Corneal Edema

Hypertonic solution for the treatment of corneal edema.

  • Patented formulation
  • High cleansing action of the tear film
  • High protective action of the ocular surface
  • More tolerable than the competitors

Riboflavin sodium phosphate, Sodium chloride (5%), Vitamin E TPGS, Sodium Hyaluronate, L-Proline, L-Glycine, L-Leucine, L-Lysine, Dibasic dodecahydrate sodium phosphate, Monohydrate monobasic sodium phosphate, purified water

  • 10 ml preservative free OSD bottle
  • Class IIB CE Medical Device
  • Shelf life: 3 years
  • Compatible with contact lenses
Drop Clar
Drop Clar logo

Antioxidant Eye Drops

Antioxidant solution that protects the crystalline lens from photo-oxidative damage, preserving its transparency.

  • Patented formulation
  • Proven antioxidant action
  • Proven protection against photo-oxidative damage on the crystalline lens
  • Long lasting action
  • Preservative free
  • Contact lenses friendly

Riboflavin Sodium Phosphate 0.05%, Sodium Chloride, Vitamin E TPGS, Sodium Phosphate Dibasic Dodecahydrate, Sodium Hyaluronate, Methylsulfonylmethane, Sodium Phosphate Monobasic Monohydrate, L-Proline, L-Glycine, L-Leucine, L-Lysine Hydrochloride, water for injections

  • 10 ml preservative free OSD bottle
  • Class IIB CE Medical Device
  • Shelf life: 3 years
  • Compatible with contact lenses

  • F. Vizzarri, M. Palazzo, S. Bartollino, D. Casamassima, B. Parolini, P. Troiano, C. Caruso, C. Costagliola, “Effects of an Antioxidant Protective Topical Formulation on Eye Exposed to Ultraviolet-Irradiation: a Study in Rabbit Animal Model.” Physiol. Res. 67: 457-464, 2018.
  • Ostacolo C, Caruso C et al. “Assessment of UV protection by chick embryo model.” Data on file.

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